Altered Erythro-Myeloid Progenitor Cells Are Highly Expanded in Intensively Regenerating Hematopoiesis
نویسندگان
چکیده
منابع مشابه
Hematopoiesis: Wandering progenitor cells
The generation of mice that are chimeric for expression of alpha 4 integrin has revealed a critical role for this adhesion molecule, specifically in postnatal lymphopoiesis.
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Development of mature blood cell progenies from hematopoietic stem cells involves the transition through lineage-restricted progenitors. The first branching point along this developmental process is thought to separate the erythro-myeloid and lymphoid lineage fate by yielding two intermediate progenitors, the common myeloid and the common lymphoid progenitors (CMPs and CLPs). Here, we use singl...
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ژورنال
عنوان ژورنال: Frontiers in Cell and Developmental Biology
سال: 2020
ISSN: 2296-634X
DOI: 10.3389/fcell.2020.00098